Bongkrekic acid-13c28

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August undefined, 2024

WebNational Center for Biotechnology Information. 8600 Rockville Pike, Bethesda, MD, 20894 USA. Contact. Policies. FOIA. HHS Vulnerability Disclosure. National Library of Medicine. National Institutes of Health. Department of Health and Human Services. WebThe bongkrekic acid is produced by Pseudomonas cocovenenans on partially defatted coconutproducts. Though a submerged culture would make a larger production much easier, it appears that no bongkrekic acid is formed, if the partially defatted coconut-product is omitted. The strong antibiotic properties of bong-

Effect of bongkrekic acid on growth and metabolism of ... - Springer

WebBongkrekic acid (BA) is a sort of fatty acid produced by the bacterium Burkholderia gladioli pv. Cocovenenans, which survives in corn flour and coconut products (Travis M Falconer et al., 2016). First documented food poisoning case due to BA happened in Indonesia in 1895. WebNov 22, 2004 · Bongkrekic acid (1) 1 is a natural toxic antibiotic produced by the microorganism Pseudomonas cocovenenans.The high toxicity of 1 has been attributed to its affinity for the ATP/ADP translocator protein residing in the mitochondrial inner membrane, which prevents oxidative phosphorylation (IC 50 = 2 × 10 −8 M). 2 Furthermore, by … bubble bass party

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WebBongkrek acid (also known as bongkrekic acid) is a respiratory toxin produced in fermented coconut or corn contaminated by the bacterium Burkholderia gladioli pathovar … WebIso-bong: A versatile first synthesis of isobongkrekic acid (IBA) has been developed. Key steps include three different palladium cross-couplings and an asymmetric homopropargylation. In-depth synthetic studies reveal the challenges faced in generating the right geometry of each diene. Abstract Webthat bongkrekic acid is an inhibitor of oxidative phosphorylation in rat heart mitochondria, and that, unexpectedly, it also ac- celerated the oxidation of succinate and /3 … explanation of miraculous medal

Determination of bongkrek acid and toxoflavin by high pressure …

WebBongkrekic acid is a little-known toxin and source of food poisoning that is produced by the bacterium Burkholderia gladioli. These bacteria flourish … WebC 28 H 38 O 7. CAS number: 11076-19-0. EU number: Not assigned. Fermentek product code: BON. Source: Pseudomonas gladioli. explanation of microwave wavesWebThe symptoms of 3-NPA toxicity in humans are similar to those for bongkrekic acid, as described regarding sugar cane poisoning in humans in China and Africa, including initial gastrointestinal symptoms with vomiting and diarrhea and progressing encephalopathy leading to coma and death (8,11,12). bubble bass order explained

"WebMay 1, 2002 · Mitochondrial Delivery of Bongkrekic Acid Using a MITO-Porter Prevents the Induction of Apoptosis in Human HeLa Cells. Journal of Pharmaceutical Sciences 2013, 102 (3) , 1008-1015. " - Bongkrekic acid-13c28

Bongkrekic acid-13c28

Bongkrekic acid solution - Sigma-Aldrich

WebJan 19, 2024 · Bongkrekic acid (BA), a little-known mitochondrial toxin produced by the bacterium Burkholderia gladioli pathovar (strain or set of strains with the same or similar … WebThe inhibitors atractyloside and bongkrekic acid trap the AACs in two different conformations known as the c- and m-state where the carrier is open to the cytoplasmic …

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WebDec 1, 2024 · Bongkrekic acid (BKA) inhibits adenine nucleotide translocator (ANT) and suppresses ADP/ATP exchange in the mitochondrial inner membrane. Previously, we … WebCHEBI:77742 - bongkrekic acid. A tricarboxylic acid that is docosa-2,4,8,10,14,18,20-heptaenedioic acid substituted at positions 2 ,5 and 17 by methyl groups, at positions 6 by a methoxy group and at position 20 by a carboxymethyl group. It is produced by the bacterium Burkholderia gladioli and implicated in outbreaks of food-borne illness ...

WebBongkrekic acid affects the liver, brain and kidneys, causing symptoms including lack of energy, dizziness, drowsiness, abdominal pain, vomiting etc. In severe cases, consuming food contaminated with Bongkrekic acid can be life threatening. What is SFA doing to reduce food safety risks from Bongkrekic Acid? WebOct 1, 1982 · INTRODUCTION Bongkrek acid and toxoflavin are toxins which became well-known in connection with cases of food poisoning by the consumption of tempe bongkrek, one of the many fermented foods in Indonesia. It is made by fermentation of partially defatted coconut with Rhizopus oligosporus.

WebBongkrekic acid C28H38O7 - PubChem Apologies, we are having some trouble retrieving data from our servers... PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville … WebPribolab®. - Model STD#1201U - U- [13C28]-Bongkrekic acid-5 µg/mL-Methanol. From Mycotoxins. Share. Mycotoxin 13C stable isotope labeled internal standards are stable, …

WebSep 20, 2024 · Bongkrekic acid is produced by the bacterium, Burkholderia cocovenenans, which is ubiquitous in the soil and plants. It grows best at 37°C and can optimally produce bongkrekic acid at about 26°C. Bongkrekic acid is heat-stable and cannot be removed by washing. Patients suffering from bongkrekic acid poisoning may show symptoms …

bubble bass sitting on planktonWebDec 18, 2024 · Poisoning incidents caused by bongkrekic acid (BA), one of the metabolites of Burkholderia gladioli pathovar cocovenenans ( B. cocovenenans ), have been reported in Indonesia, Mozambique, and China. The reported case fatality rates averaged 60%, 32%, and 26.5%, respectively. explanation of micah 1WebJan 1, 2024 · Consumption of sufficient quantities of bongkrekic acid initially results in hyperglycemia, followed quickly by hypoglycemia that depletes the glycogen reserves in various tissues, including the heart and liver [5].A variety of symptoms are observed 4–6 h after consumption before lapsing into a coma, with death occurring 1–20 h after symptom … explanation of midsommarWebJan 19, 2024 · Bongkrekic acid is a heat-stable, highly unsaturated tricarboxylic fatty acid with a molecular weight of 486 kDa. Outbreaks have been reported from Indonesia, … explanation of microsoft appsWebFigure 2. Chemical structure of Bongkrekic acid C28H38O7 3.2 Relationship between Bongkrekic acid and fermented corn food From 1951 to 2014, up to 9336 people in … bubble bass s orderWebFor example, bongkrekic acid, or exposure to uncouplers such as p -trifluoromethoxy carbonyl cyanide phenyl hydrazone (FCCP) to moderate Ca 2+ uptake during excitotoxicity, correspondingly moderate mitochondrial dysfunction and cell death in the short term. 105,106 However, by preventing mitochondrial adenylate exchange, and by uncoupling … explanation of mirrorlessWebMolecular Weight: 486.61 (free acid) Molecular Formula: C 28 H 38 O 7 Solubility: Miscible with DMSO. Physical Properties: Solution at 1 mg/mL (2 mM) in 0.01M Tris buffer pH 7.5 (contains 1 mg net bongkrekic acid per mL) Purity: 97% by HPLC NMR (Conforms) Storage Temperature: -20° Stability: Stable for 1 year from date of purchase as supplied. explanation of microscope